牛玉娜，1982.01-，中山大學(xué)動物學(xué)博士學(xué)位。目前研究方向?yàn)榉肿用庖邔W(xué)，主要從事成人T淋巴細(xì)胞白血病病毒1型感染HTLV-1致白血病ATL機(jī)制研究、以及NK細(xì)胞活性調(diào)控分子機(jī)制研究。 主持國家自然科學(xué)基金青年項(xiàng)目1項(xiàng)，河南省自然科學(xué)基金1項(xiàng)；在Carcinogenesis、Immunology等雜志上發(fā)表論文17篇。
主持的科研項(xiàng)目： 河南省自然科學(xué)基金，EVI1通過調(diào)控自噬參與白血病干細(xì)胞的干性維持，2016-2018,10萬元，項(xiàng)目編號162300410213，主持人 國家自然科學(xué)基金，BCL3通過STAT3調(diào)控NK細(xì)胞的功能和機(jī)制研究，2018/1/1-2020/12/30，20萬元，項(xiàng)目編號81701554，主持人
發(fā)表SCI論文一覽表（#為第一作者，*為通訊作者） Yuna Niu#, Xue Yang, Yifei Chen, Xinyue Jin, Li Li, Yilin Guo, Xuelu Li, Yecheng Xie, Yun Zhang, Hui Wang. EVI1 induces autophagy to promote drug resistance via regulation of ATG7 expression in leukemia cells. Carcinogenesis. 2019 (accepted) Yuna Niu#, Xue Yang, Yifei Chen, Linbo Zhang, Xinyue Jin, Youjing Tang, Li Li, Lu Yu, Yilin Guo, Hui Wang. BCL3 expression is a potential prognostic and predictive biomarker in acute myeloid leukemia of FAB Subtype M2. Pathol Oncol Res. 2019 Apr;25(2):541-548. doi: 10.1007/s12253-018-0476-7. Yuna Niu#, Xue Yang, Yifei Chen, Xinyue Jin, Yecheng Xie ,Youjing Tang, Li Li, Shibo Liu, Yilin Guo, Xuelu Li, Liangwei Duan, Hui Wang. Distinct prognostic values of Annexin family members expression in acute myeloid leukemia. Clin Transl Oncol. 2019 Jan 29. [Epub ahead of print] Yuna Niu#, Qingqing Liu, Suping Zhang, Na Yuan, Yan Cao, Jinyang Cai, Weiwei Lin, Fei Xu, Zhen Wang, Jianrong Wang. Alternative messenger RNA splicing of autophagic gene Beclin 1 in human B-cell acute lymphoblastic leukemia cells. Asian Pac J Cancer Prev. 2014;15(5):2153-8. Yuna Niu#, Delin Mo, Limei Qin, Chong Wang, Anning Li, Xiao Zhao, Xiaoying Wang, Shuqi Xiao, Qiwei Wang, Ying Xie, Zuyong He, Peiqing Cong, Yaosheng Chen*. Lipopolysaccharide-induced miR-1224 negatively regulates tumour necrosis factor-α gene expression by modulating Sp1. Immunology. May;133(1):8-20. doi: 10.1111/j.1365-2567.2010.03374.x. Epub Feb 14. 2011 李莉, 張藝博, 張林波, 湯友靜, 陳逸飛, 關(guān)丫丫, 牛玉娜*. BCL3基因敲除對線粒體呼吸作用及ATP合成的影響. 中國細(xì)胞生物學(xué)學(xué)報(bào), 2018, 40(4): 533-541 張林波,牛玉娜, 王輝. 信號轉(zhuǎn)導(dǎo)與轉(zhuǎn)錄激活因子和腫瘤微環(huán)境對自然殺傷細(xì)胞功能及免疫監(jiān)視影響的研究進(jìn)展. 新鄉(xiāng)醫(yī)學(xué)院學(xué)報(bào), 2017, 34(11), 1037-1039 湯友靜, 牛玉娜, 王輝. Pink1/Parkin介導(dǎo)的線粒體自噬分子機(jī)制. 中國細(xì)胞生物學(xué)學(xué)報(bào), 2017, 39(7), 939-946 Yun Zhang, Wenqing Tan, Lin Zhang, Shuyou Shi, Yuna Niu, Xue Yang, Jinjuan Qiao, Hui Wang. Highly sensitive and selective colorimetric determination of Staphylococcus aureus via chicken anti-protein A IgY antibody. Analytical Methods, 2019 11(29), 3665-3670 Zhijian Wang, Fei Xu, Na Yuan, Yuna Niu, Weiwei Lin, Yan Cao, Jinyang Cai, Lin Song, Xin Li, Yixuan Fang, Wenli Zhao, Shaoyan Hu, Suning Chen, Suping Zhang, Jianrong Wang. Rapamycin inhibits pre-B acute lymphoblastic leukemia cells by downregulating DNA and RNA polymerases. Leuk Res. 2014 Aug;38(8):940-7. doi: 10.1016/j.leukres.2014.05.009. Epub 2014 May 24. Suping Zhang, Yuna Niu, Na Yuan, Aihong Zhang, Dan Chao, Qiuping Xu, Lijun Wang, Xueguang Zhang, Wenli Zhao, Yun Zhao, Jianrong Wang. Role of autophagy in acute myeloid leukemia therapy. Chinese Journal of Cancer; doi: 10.5732/cjc.012.10073. 2012 Limei Qin, Yaosheng Chen, Yuna Niu, Weiquan Chen, Qiwei Wang, Shuqi Xiao, Anning Li, Ying Xie, Jing Li, Xiao Zhao, Zuyong He, Delin Mo. A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway. BMC Genomics. May 23;11:320. 2010 Shuqi Xiao, Jianyu Jia, Delin Mo, Qiwei Wang, Limei Qin, Zuyong He, Xiao Zhao, Yuankai Huang, Anning Li, Jingwei Yu, Yuna Niu, Xiaohong Liu, Yaosheng Chen Y. Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing*. PLoS One. Jun 29;5(6):e11377. 2011 Shuqi Xiao, Delin Mo, Qiwei Wang, Jianyu Jia, Limei Qin, Xiangchun Yu, Yuna Niu, Xiao Zhao, Xiaohong Liu, Yaosheng Chen. Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling. BMC Genomics. Oct 7;11:544. 2010 Xiao Zhao, Delin Mo, Anning Li, Wen Gong, Shuqi Xiao, Yue Zhang, Limei Qin, Yuna Niu, Yunxue Guo, Xiaohong Liu, Peiqing Cong, Zuyong He, Chong Wang, Jiaqi Li, Yaosheng Chen. Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. PLoS One. 6(5):e19774. Epub 2011 May 26. 2011 Anning Li, Yaosheng Chen, Xiao Zhao, Yuna Niu, Peiqing Cong, Zongwu Zhang, Weiquan Chen, Wei Jiang, Delin Mo. Characterization and transcriptional regulation analysis of the porcine TNFAIP8L2 gene. Mol Genet Genomics. Epub. Sep;284(3):185-95. Jul 17. 2010 Zhisheng Zhang, Delin Mo, Peiqing Cong, Zuyong He, Fei Ling, Anning Li, Yuna Niu, Xiao Zhao, Chunyan Zhou, Yaosheng Chen. Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene. Mol Biol Rep. Mar;37(3):1611-8. 2010
主持的科研項(xiàng)目： 河南省自然科學(xué)基金，EVI1通過調(diào)控自噬參與白血病干細(xì)胞的干性維持，2016-2018,10萬元，項(xiàng)目編號162300410213，主持人
國家自然科學(xué)基金，BCL3通過STAT3調(diào)控NK細(xì)胞的功能和機(jī)制研究，2018/1/1-2020/12/30，20萬元，項(xiàng)目編號81701554，主持人
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